The Overseas Pharmacist Readiness Assessment (OPRA) exam has officially replaced the Knowledge Assessment of Pharmaceutical Sciences (KAPS) exam as of March 2025. This transition marks a significant shift in the way international pharmacists are assessed for registration in Australia.

If you're an overseas-trained pharmacist looking to practice in Australia, understanding the new OPRA exam format, difficulty level, and preparation strategies is crucial for your success. This guide breaks down everything you need to know.

The Australian Pharmacy Council (APC) designed OPRA to better reflect the real-world application of pharmacy knowledge, especially in therapeutics and patient care. The goal is to ensure that overseas pharmacists can confidently handle clinical scenarios, make informed therapeutic decisions, and seamlessly integrate into the Australian healthcare system.

The new OPRA exam is shorter but more intense, requiring a deeper understanding of pharmacotherapeutics, patient-centered care, and real-world problem-solving.

Both exams assess pharmaceutical knowledge, but OPRA has a stronger focus on therapeutics, clinical judgment, and applied pharmacy practice.

• Stronger Focus on Therapeutics – You must understand drug interactions, adverse effects, and appropriate medication management.

• More Clinical Scenarios – Expect case-based questions that test your decision-making skills rather than just theoretical knowledge.

• Emphasis on Patient Safety – The exam evaluates how well you can ensure patient well-being in a pharmacy setting.

For pharmacists who are more accustomed to memorization-based exams, this new format may feel challenging at first. However, those with practical experience in patient care will find OPRA more aligned with real-world pharmacy practice.

The Australian Pharmacy Council (APC) states that the difficulty level of OPRA remains similar to KAPS. However, candidates have mixed opinions.

• Easier for Those with Clinical Experience: Pharmacists who have hands-on experience in patient counseling, drug therapy management, and hospital or retail pharmacy work may find the OPRA exam manageable.

• Harder for Theoretical Learners: Those who relied on pure memorization for KAPS may struggle with OPRA, as it demands critical thinking and decision-making skills.

Succeeding in the OPRA exam requires a strategic approach. Here’s how you can prepare effectively:

1. Understand the Exam Format

   • Familiarize yourself with OPRA’s question structure and focus areas. Since it includes clinical scenarios, practice answering case-based MCQs.

2. Strengthen Your Therapeutics Knowledge

   • Revise common disease conditions, treatment guidelines, drug interactions, and adverse effects. Australian guidelines like the Therapeutic Guidelines (eTG) and APF (Australian Pharmaceutical Formulary) are must-reads.

3. Use Updated Study Materials

   • Ensure you’re using OPRA-specific study guides, mock exams, and review courses. Many old KAPS materials may not be sufficient.

4. Practice with AI-Based Mock Tests

   • Taking AI-driven mock exams will help you understand the types of questions and boost confidence.

5. Join OPRA Preparation Groups

   • Engage in study groups and discussion forums to exchange knowledge and strategies with other test-takers.

The OPRA exam represents a positive change for overseas pharmacists aiming to register in Australia. It aligns more closely with the realities of pharmacy practice and ensures that international pharmacists are well-prepared for patient-centered care.

✅ Less memorization, more application
✅ Better reflects real-world pharmacy practice
✅ Prepares pharmacists for immediate job readiness

While the exam structure has changed, the goal remains the same—to ensure that pharmacists meet the standards required to provide safe and effective healthcare in Australia.

If you're planning to take the OPRA exam, start preparing now with the right resources and a strong focus on therapeutics and clinical reasoning.

Get expert guidance on OPRA exam Preparation, study materials, and AI-powered mock tests with Academically Global. Enroll now and take the first step toward your Australian pharmacy career!